caching - Are block sizes fixed in hardware or can be reprogrammed in C or asm? -

i focus on c , assembly , i'm reading various uses of various block sizes e.g. caching, buffering , likewise. block size used in same way in buffering in cacheing , block size # definein c-code how buffer when buffered i/o? or block size somehow fized in hardware , can't manipulated programmer? other uses of blocks caching , buffering?

block size set operating system , can specified when creating file system. instance, have block sizes of 4096kb in ntfs partition, , page file located on partition. therefore, pages correspond these blocks of size 4096kb.